The medicine "Tsefazolin". Instructions for use. Nyxes: features of intramuscular and intravenous administration
The drug "Cefazolin" (injections), the price of which is from 90up to 465 rubles, is an antimicrobial semisynthetic agent. The medicine is a powder. From it, a solution for injection is prepared. The introduction is carried out intravenously or intramuscularly. The active substance is cefazolin sodium salt.
Properties of the tool
The drug "Cefazolin" is considered the most non-toxiccephalosporin antibiotic. Together with this, it has a pronounced bactericidal activity. The drug inhibits the activity of gram-positive bacteria, both synthesizing and not synthesizing penicillinase, as well as strains of gram-negative microflora. An hour after the introduction of the muscle, the maximum concentration of the drug is noted. With intravenous injection - instantly.
According to the information that contains the drug"Tsefazolin" instructions for use, injections are recommended for pathologies of an infectious nature, caused by the activity of pathogenic bacteria that show sensitivity to the medication. Indications include lesions of bones and joints, skin, soft tissues. Assign a remedy for empyema of the pleura, osteomyelitis, endocarditis. Injections are recommended for patients with infected wounds, burns. Effective medication in the postoperative period for the prevention of complications. Indications are also inflammatory processes of an infectious nature in the urinary system, pneumonia, abscess in the lungs, peritonitis.
Dosage regimen of the drug "Cefazolin" (injections). How to grow a medicine
The medication is intended for intramuscular orintravenous (jet or drip) administration. In accordance with the recommendations that contains instruction for the preparation "Cefazolin", injections into the muscle are carried out after mixing the contents of the vial with 5 milliliters of sodium chloride (isotonic solution) or water for injection. The drug is injected deep into the tissue. For intravenous fluid infusion, a single dose is prepared by diluting the drug in 8-10 ml of sodium chloride (isotonic solution). Enter the medication slowly, for four or five minutes. Injections by a drop method are carried out by a diluted preparation in a glucose solution of a five percent concentration or in 150-250 milliliters of sodium chloride. In this case, the infusion is carried out for thirty minutes. The speed at the introduction is 65-80 cap / min. The daily dosage for adults is 1000-4000 mg. The amount of the drug depends on the severity of the infection and the sensitivity of the pathogen. Taking into account the information on the instructions for use about the preparation "Cefazolin", injections to children are prescribed in accordance with the weight. The daily dose is 20-50 mg / kg, in cases of severe disease - 100 mg / kg.
Contraindications to the drug
No medication is prescribed during breastfeeding,with hypersensitivity, during prenatal period. According to the information contained in the instruction manual for the use of Cefazolin, injections are not allowed for children until the month of life.